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C7905-02-ML490 C-Peptide (MaxLight 490)

Specifications
References
Brand
MaxLight™
Conjugate
MaxLight™490
Specificity
Recognizes human C-peptide of proinsulin. Does not react with insulin or other peptide hormones.
Source Antibody
human
Purity
Purified by Protein A affinity chromatography.
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free

MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000.

C-Peptide is part of the molecule of Proinsulin, that consists of three parts: C-Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C-Peptide are produced C-peptide is released into the bloodstream in equal amounts to insulin. A test of C-peptide levels will show how much insulin the body is making.
Applications
Suitable for use in FLISA, RIA, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended Dilution
Immunohistochemistry: paraffin sections Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
References
1. Hilgert I, Stolba P, Kristofova H, Stefanova I, Bendlova B, Lebl M, Horejsi V: A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA. Hybridoma. 1991 Jun; 10(3):379-86. 2. Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Martinez Casals A, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, Fisher J, Livengood AJ, Dowell KG, Silverstein JC, Spraggins JM, Pryhuber GS, Deutsch G, Ginty F, Nolan GP, Melov S, Jonigk D, Caldwell MA, Vlachos IS, Mueller W, Gehlenborg N, Stockwell BR, Lundberg E, Snyder MP, Germain RN, Camarillo JM, Kelleher NL, Börner K, Radtke AJ: Organ mapping antibody panels: a community resource for standardized multiplexed tissue imaging. Nat Methods 2023 Aug; 20(8):1174-1178. doi: 10.1038/s41592-023-01846-7.
USBio References
No references available
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