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C7907-02 C-Reactive Protein, Rat (CRP, MGC88244, PTX 1, PTX1) BioAssay™ ELISA Kit

Specifications
References
Brand
BioAssay™
Kit Type
ELISA
Tests
96
Sample Volume
100ul
Sensitivity
2ng/ml
Detection Method
Colorimetric
Sample Matrix
Plasma or serum
EU Commodity Code
38220000
UN DOT Shipping
UN2796 PGII
Shipping Temp
Blue Ice
Storage Temp
4°C

C-reactive protein (CRP) has been regarded as an acute phase reactant in serum. It consists of five single subunits, which noncovalently linked and assembled, as a cyclic pentamer with a MW. Range of 110-140kD. CRP has been found to be increased in serum of patients with a wide variety of diseases including infections by gram-positive and gram-negative bacteria, acute phase of rheumatoid arthritis, abdominal abscesses, inflammation of bile ducts, myocardial infarction, and malignant tumors. CRP may be found in patients with Guillain-Barre syndrome and multiple sclerosis, certain viral infections, tuberculosis, acute infectious hepatitis, many other necrotic and inflammatory diseases, burned patients, and after surgical trauma. Although the detection of elevated levels of CRP in the serum is not specific for any particular disease, it is useful indicator of inflammatory processes. CRP levels rise in serum within hours of the onset of inflammation, reach a peak during the acute stage and decrease with resolution of inflammation trauma. The detection of CRP is a more reliable and sensitive indicator of the inflammatory process than the erythrocyte sedimentation rate, which may also be influenced by physiological changes not associated with an inflammation process. Current quantification methods including latex agglutination, nephelometry, radial immunodiffusion have the general disadvantage accompany agglutination and precipitation techniques.

US Biological’s rat CRP ELISA provides is a rapid, specific and sensitive assay for CRP in rat plasma or serum.
Kit Components
C7907-02A: CRP Microtiter Plate 1x96wells C7907-02B: CRP Standard 2.5ng/ml 1x650ul C7907-02C: CRP Standard 5ng/ml 1x650ul C7907-02D: CRP Standard 10ng/ml 1x650ul C7907-02E: CRP Standard 20ng/ml 1x650ul C7907-02F: CRP Standard 60ng/ml 1x650ul C7907-02G: Wash Buffer (10X) 1x10ml C7907-02H: Sample Diluent (20X) 1x10ml C7907-02J:. CRP (HRP) 1x150ul C7907-02K: TMB Substrate 1x12ml C7907-02L: Stop Solution 1x12ml C7907-02M: Positive Control 1x650ul
Storage and Stability
Store at 4°C. Stable for 6 months.
References
1. Powell, L., et al., Am. J. Med. Technol. 87: 138 (1979). 2. Osmand, A.P., PNAS 74: 739 (1977). 3. Ash, R., et al., J. Infec. Immunity 53: 89 (1983). 4. Hedlulnd, et al., Acta. Med. Scan. 128: 579 (1947). 5. Kushner, I., et al., J. Clin. Invest. 61: 235 (1978). 6. Hedlulnd, P., et al., Acta. Med. Scan. 169: 1 (1961). 7. Yocum, S., et al., Arch. Intern. Med. 99: 74 (1957). 8. Dowling, P., in Multiple Sclerosis, AP, pp269 (1972). 9. Roantree, R.J., et al., Arch. Int. Med. 96: 674 (1955). 10. Morley, J.J., et al., Ann. NY Acad. Sci. 389: 406 (1982). 11. Claus, D.R., J. Lab. Clin. Med. 87: 120 (1976).
USBio References
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