Progesterone

Specificity

Recognizes Progesterone. Does not cross react with cortisol, estradiol, estriol or testosterone.

Purity

Purified by Protein A affinity chromatography.

EU Commodity Code

30021010

Shipping Temp

Blue Ice

Storage Temp

-20°C

Progesterone is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta in order to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Progesterone is available as a pharmaceutical that can be used to treat menstrual disorders and for the prevention of miscarriage.

Applications

Suitable for use in ELISA, Immunohistochemistry and RIA. Other applications not tested.

Recommended Dilutions

Immunohistochemistry: Paraffin Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

References

1. Cahill, D. J. et al. (2003) Pre-ovulatory granulosa cells of infertile women with endometriosis are less sensitive to luteinizing hormone. Am. J. Reprod. Immunol. 49: 66-69.