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461645 Oseltamivir

Specifications
References
Grade
Highly Purified
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
(-)-Oseltamivir; Enfluvir; Ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate; GOP-A-Flu; GS 4104; Oseltamivir; Tamiflu-Free; Tamvir

Oseltamivir is an orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug. It is a COVID19-related research product.

Synonyms
(-)-Oseltamivir; Enfluvir; Ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate; GOP-A-Flu; GS 4104; Oseltamivir; Tamiflu-Free; Tamvir
CAS No
196618-13-0
Molecular Formula
C₁₆H₂₈N₂O₄
Molecular Weight
312.40
Purity (HPLC)
≥96%
Appearance
Off-white to pale beige solid
Solubility
Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Melting Point
108-110°C (lit)
Method for Determining Identity
Proton NMR Spectroscopic Analysis and Mass Spectrometric Analysis
TLC Conditions
C18; Acetonitrile: Water: Ammonium Hydroxide =8:2:0.1; Visualized with UV and KMnO4; Single spot; Rf= 0.40
Elemental Analysis
Calculated: %C: 61.51, %H: 9.03, %N: 8.97
Specific Rotation (c=1.0, Chloroform)
As Reported
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20ºC for 6 months after time of receipt. Hygroscopic
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Oliyai, R., et al.: Pharm. Res., 15, 1300 (1998). 2. Kim, C.U., et al.: Med. Chem. Res., 8, 392 (1998). 3. Hayden, F.G., et al.: N. Engl. J. Med., 341, 1336 (1999). 4. Treanor, J.J., et al.: J. Am. Med. Assoc., 283, 1016 (2000)
USBio References
No references available
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