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G8972-15 GRK 4-6

Specifications
References
Grade
Purified
Purity
Purified by ammonium sulfate precipitation
Form
Supplied as liquid in 0.1M Tris-glycine, pH 7.0, 0.05% sodium azide.
Specificity
Recognizes GRK 4, GRK 5 and GRK 6. Species Crossreactivity: Human, mouse and rat.
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
-20°C

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension.

Applications
Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
References
General Freedman, N.J., et al., J. Biol. Chem. 272: 17734-11743, 1997. Pitcher, J.A., et al., J. Biol. Chem. 271: 24907-24913, 1996. Nagayama, Y., et al., J. Biol. Chem. 271: 10143-10148, 1996. Application Oppermann, M., et al., Proc. Natl. Acad. Sci. USA 93: 7649-7654, 1996.
USBio References
No references available
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