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H7980-36A Hyaluronic Acid Binding Protein 1, Recombinant, Human, aa74-282 (Hyaluronan Binding Protein 1, HABP1, C1qBP, C1q-R, Human Complement Component 1, q Subcomponent Binding Protein)

Specifications
References
Grade
Highly Purified
Purity
≥95% by SDS PAGE. Endotoxin: ≤1EU/ug (LAL)
Form
Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 1mM DTT, 20% glycerol
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C
p32, HABP1, gC1qR, GC1QBP, SF2p32

Human complement component 1, q subcomponent binding protein (C1QBP) is a ubiquitously expressed multifunctional phospho-protein that interacts with the globular heads of C1q (gC1q). This protein also interacts with a wide range of ligands and is implicated in cell signaling.

Recombinant, protein corresponding to aa74-282 from human HABP1, expressed in E. coli. Accession: NP_001203
Molecular Weight
23.9kD (210aa)
Amino Acid Sequence
MLHTDGDKAF VDFLSDEIKE ERKIQKHKTL PKMSGGWELE LNGTEAKLVR KVAGEKITVT FNINNSIPPT FDGEEEPSQG QKVEEQEPEL TSTPNFVVEV IKNDDGKKAL VLDCHYPEDE VGQEDEAESD IFSIREVSFQ STGESEWKDT NYTLNTDSLD WALYDHLMDF LADRGVDNTF ADELVELSTA LEHQEYITFL EDLKSFVKSQ
Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Concentration
~1mg/ml
Form
Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 1mM DTT, 20% glycerol
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Fogal, V., et al., Cancer Res. 68(17): 7210-7218 (2008). 2. Biswas, A.K., et al., PLoS Pathog. 3(9): 1271-1280 (2007). General References: 1. Thakur, S.C., et al., J. Androl. 27: 604 (2006). 2. Peerschke, E.I.B. & Ghebrehiwet, B., Immunobiology 212: 333 (2007). 3. Lynch, N.J., et al., FEBS Lett. 418: 111 (1997). 4. Jiang, J., et al., Proc. Natl. Acad. Sci. 96: 3572 (1999). 5. Rozanov, D.V., et al., J. Biol. Chem. 277: 9318 (2002). 6. Deb, T.B. & Datta, K., J. Biol. Chem. 271: 2206 (1996). 7. Lim, B.L., et al., J. Biol. Chem. 271: 26,739 (1996). 8. Grebrehiwet, B., et al., J. Exp. Med. 179: 1809 (1994). 9. Waggoner, S.N., et al., J. Leukoc. Biol. 82: epub (2007). 10. Innamorati, G., et al., Cell. Signal. 18: 761 (2006). 11. Robles-Flores, M., et al., J. Biol. Chem. 277: 5247 (2002). 12. Sunayama, J., et al., Cell Death Differ. 11: 771 (1994). 13. Pupo, A.S. & Minneman, K.P., J. Recept. Signal Transduct. 23(2-3): 185-195 (2003). 14. Schaerer, M.T., et al., J. Biol. Chem. 276: 26,597 (2001). 15. Peterson-Mahrt, S.K., et al., EMBO J. 18: 1014 (1999). 16. Chattopadhyay, C., et al., Nucleic Acids Res. 32: 3632 (2004). 17. Majumdar, M., et al., Biochem. Biophys. Res. Commun. 291(4): 829-837 (2002).
USBio References
No references available
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