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138617 CAB39L, Recombinant, Human, aa1-337, His-Tag (Calcium-binding Protein 39-like, MO25-BETA, MO2L) CAS:

Specifications
References
Grade
Highly Purified
Molecular Weight
41.5
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

Calcium-binding protein 39-like, also known as CAB39L, is similar to MO25 and is found in the serum of nearly half of all patients diagnosed with acute monocytic leukemia. This protein suggests a role for CAB39L in carcinogenesis. Also, LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the CAB39L.

Source
Recombinant protein corresponding to aa1-337 from human CAB39L at N-terminal, fused to His-tag expressed in E.coli.
Molecular Weight
~41.5kD (360aa)
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMKKMPLF SKSHKNPAEI VKILKDNLAI LEKQDKKTDK ASEEVSKSLQ AMKEILCGTN EKEPPTEAVA QLAQELYSSG LLVTLIADLQ LIDFEGKKDV TQIFNNILRR QIGTRSPTVE YISAHPHILF MLLKGYEAPQ IALRCGIMLR ECIRHEPLAK IILFSNQFRD FFKYVELSTF DIASDAFATF KDLLTRHKVL VADFLEQNYD TIFEDYEKLL QSENYVTKRQ SLKLLGELIL DRHNFAIMTK YISKPENLKL MMNLLRDKSP NIQFEAFHVF KVFVASPHKT QPIVEILLKN QPKLIEFLSS FQKERTDDEQ FADEKNYLIK QIRDLKKTAP
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥95% (SDS-PAGE)
Concentration
~0.5mg/ml
Form
Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.1M sodium chloride, 1mM DTT, 10% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Boudeau J., et al. (2004) J Cell Sci. 117:6365-6375. 2. Taylor E B., et al. (2005) Am J Physiol Endocrinol Metab. (288):E1055-1061.
USBio References
No references available
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