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351221 FGF21, Recombinant, Mouse, aa29-210, His-Tag|(Fibroblast growth factor 21) CAS:

Specifications
References
Grade
Purified
Accession Number
NP_064397
Molecular Weight
21
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C/-70°C

FGF21, also known as fibroblast growth factor 21, is a member of the fibroblast growth factor family. It has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. It stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression.

Recombinant protein corresponding to aa29-210 from mouse FGF21, fused to His-tag at C-terminal expressed in Insect cell.
Molecular Weight
~21kD (190aa)
Amino Acid Sequence
AYPIPDSSPL LQFGGQVRQR YLYTDDDQDT EAHLEIREDG TVVGAAHRSP ESLLELKALK PGVIQILGVK ASRFLCQQPD GALYGSPHFD PEACSFRELL LEDGYNVYQS EAHGLPLRLP QKDSPNQDAT SWGPVRFLPM PGLLHEPQDQ AGFLPPEPPD VGSSDPLSMV EPLQGRSPSY ASLEHHHHHH
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, insect cell line
Concentration
~0.5mg/ml
Form
Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Kharitonenkov A., et al. (2005) J Clin Invest. 115:1627-1635. 2. Yamauchi H., et al. (2006) EMBO Rep. 7:649-654.
USBio References
No references available
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