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O7500-10 Orexin A, Mouse, Control Peptide (Hypocretin A) CAS:

Specifications
References
Grade
Highly Purified
Applications
E
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Control Peptide for O7500 (antiserum) and O7500-05 (affinity purified)

Synthetic peptide, 18aa, amino terminus of murine Orexin A. Hypothalamic neuropeptides associated with feeding behavior, binding and activating two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Recognizes the full-length (1-33 aa) Orexin-A. The epitope is not found in Orexin B. Since Orexin A and Orexin B are derived from an unprocessed pre-pro-orexin (130 aa), anti-Orexin A antibodies may also react with prepro orexins. Antibody crossreactivity in various species is not established, although murine Orexin A peptide is 100% homologous in mouse, rat, and human.
Applications: Suitable for use as a control in ELISA and antibody blocking.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Mouse, synthetic peptide
Purity
Highly purified
Concentration
~1mg/ml
Form
Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Sa1. Sakurai, T. et al. (1998) Cell, 92, 573–585. 2. DeLecca L et al (1998) PNAS 95, 322–327. 3. Ciriello J, 2003, Brain Research, 967, 123-131. 4. Ouedraogo R., 2003, Diabetes, Jan 2003; 52: 111- 117. 5. deOliveira CVR, 2003, Am J Physiol Heart Circ Physiol 284: H1369. 6. Satoh S, 2003, Eur. J. Neuroscience 17, 1635. 7. Davis SF, 2003, J. Neurosci., 23: 3844 - 3854. 8. Ciriello J, 2003, Brain Research, 991, 84-95. 9. Ehrstrom M., 2003, Am J Physiol Gastrointest Liver Physiol, 285, 688. 10. Ciriello J, 2003, Am J Physiol Regul. Int. Comp Physiol, 284: 1611. 11. deOliveira CVR, 2003, Brain Research 978, 14-23.
USBio References
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