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032039 Rabbit Anti-ARHGAP24, CT (ARHGAP24, FILGAP, Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, RAC1- and CDC42-specific GTPase-activating protein of 72kD, Rho-type GTPase-activating protein 24, RhoGAP of 73kD, Sarcoma antigen NY-SAR-88, p73RhoGAP)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8N264
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001020787.2; NP_112595.2; NP_001036134.1
Gene ID
83478
Gene #
ARHGAP24
Shipping Temp
Blue Ice
Storage Temp
-20°C
ARHGAP24, FILGAP, Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, RAC1- and CDC42-specific GTPase-activating protein of 72kD, Rho-type GTPase-activating protein 24, RhoGAP of 73kD, Sarcoma antigen NY-SAR-88, p73RhoGAP

ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 587-616 in the C-terminal region of human ARHGAP24, Swiss/UniProt Accession: Q8N264
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ARHGAP24.
References
1. Horinouchi, M., et al. Pediatr Hematol Oncol 27(5):344-354(2010) 2. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : 3. Holm, H., et al. Nat. Genet. 42(2):117-122(2010) 4. Pfeufer, A., et al. Nat. Genet. 42(2):153-159(2010) 5. Nakamura, F., et al. PLoS ONE 4 (3), E4928 (2009) :
USBio References
No references available
Conjugates
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