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035592 Rabbit Anti-FCRL4, CT (FCRL4, FCRH4, IFGP2, IRTA1, Fc receptor-like protein 4, Fc receptor homolog 4, IFGP family protein 2, Immune receptor translocation-associated protein 1, CD307d)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q96PJ5
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Gene ID
83417
Gene #
FCRL4
Shipping Temp
Blue Ice
Storage Temp
-20°C
FCRL4, FCRH4, IFGP2, IRTA1, Fc receptor-like protein 4, Fc receptor homolog 4, IFGP family protein 2, Immune receptor translocation-associated protein 1, CD307d

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.

Applications
Suitable for use in Western Blot, ELISA and Indirect Flow Cytometry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:2000 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 480-507 in the C-terminal region of human FCRL4.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human FCRL4.
References
1. Davila, S., et al. Genes Immun. (2010) In press : 2. Weiss, G.E., et al. J. Immunol. 183(3):2176-2182(2009) 3. Kazemi, T., et al. Cancer Immunol. Immunother. 58(6):989-996(2009) 4. Falini, B., et al. Blood 102(10):3684-3692(2003)
USBio References
No references available
Conjugates
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