MAFB, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q9Y5Q3

Isotype

IgG

Grade

Affinity Purified

Applications

E FC WB

Crossreactivity

Accession #

NP_005452.2

Gene ID

9935

Gene #

MAFB

Shipping Temp

Blue Ice

Storage Temp

-20°C

MAFB, KRML, Transcription factor MafB, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq].

Applications

Suitable for use in ELISA, Western Blot and Indirect Flow Cytometry. Other applications have not been tested.

Recommended Dilution

Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 266-292 in the C-terminal region of human MAFB. Species Sequence Homology: monkey, mouse, rat, Xenopus

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human MAFB.

References

1. Kim, H., et al. Nat. Immunol. 11(8):743-750(2010) 2. Beaty, T.H., et al. Nat. Genet. 42(6):525-529(2010) 3. Vatsveen, T.K., et al. Leuk. Res. 33(12):1670-1677(2009) 4. Zanocco-Marani, T., et al. Exp. Cell Res. 315(11):1798-1808(2009) 5. Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)

USBio References

1. Hasan S., et al. Myelo-erythroid commitment after burn injury is under β-adrenergic control via MafB regulation. 2017. Am J Physiol. 312(3):C286-C301.

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038061 Rabbit Anti-MAFB, CT (MAFB, KRML, Transcription factor MafB, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

MAFB, KRML, Transcription factor MafB, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B

References

USBio References

Conjugates

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