IL-1 beta, Interleukin-1 beta, IL-1ß, catabolin

IL-1B (also known as Interleukin-1B, IL-1B and catabolin) is produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1B is a monomeric secreted protein that may be released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. IL-1B is ideal for investigators involved in cardiovascular and immunology research.