RLBP1, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

P12271

Isotype

IgG

Grade

Affinity Purified

Applications

Crossreactivity

Hu Mo

Shipping Temp

Blue Ice

Storage Temp

-20°C

Retinaldehyde-binding protein 1, Cellular retinaldehyde-binding protein, RLBP1, CRALBP|

Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'.

Applications

Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution

Western Blot: 1:2000 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within aa255-288 from human RLBP1.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human RLBP1. Species Crossreactivity: mouse

References

1. Crabb J.W.,et al.J. Biol. Chem. 263:18688-18692(1988).|2. Intres R.,et al.J. Biol. Chem. 269:25411-25418(1994).|3. Ota T.,et al.Nat. Genet. 36:40-45(2004).|4. Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.|5. Crabb J.W.,et al.Protein Sci. 7:746-757(1998).

USBio References

No references available

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378612 Rabbit Anti-RLBP1, CT

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Shipping Temp

Storage Temp

Retinaldehyde-binding protein 1, Cellular retinaldehyde-binding protein, RLBP1, CRALBP|

References

USBio References

Conjugates

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