DDA1

Clone Type

Polyclonal

Host

Goat

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

Crossreactivity

Ca Hu Mo

Accession #

NP_076955.1

Gene ID

79016, 66498

Shipping Temp

Blue Ice

Storage Temp

-20°C

May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD-E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins.

Applications

Suitable for use in ELISA. Other applications not tested.

Recommended Dilution

ELISA: 1:32,000 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Synthetic peptide corresponding to C-PSVYLPTREYP, from DDA1, at the internal region of the protein (NP_076955.1).

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity

Purified by immunoaffinity chromatography.

Specificity

Recognizes DDA1. Species sequence homology: Canine, human and mouse.

References

1. Olma MH, Roy M, Le Bihan T, Sumara I, Maerki S, Larsen B, Quadroni M, Peter M, Tyers M, Pintard L, An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases. J Cell Sci. 2009 Apr 1;122(Pt 7):1035-44.

USBio References

No references available

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D1559-93 Goat Anti-DDA1 (DET1- and DDB1-associated Protein 1, Placenta Cross-immune Reaction Antigen 1, PCIA-1, C19orf58, PCIA1)

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