Guanylate Cyclase alpha-2, Soluble, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Isotype

IgG

Grade

Purified

Applications

E IHC WB

Crossreactivity

Accession #

NP_000846

Shipping Temp

Blue Ice

Storage Temp

-20°C

EC=4.6.1.2

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.

Applications

Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:50-1:200 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Synthetic peptide selected from the C-terminal region of human GUCY1A2 (KLH).

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity

Purified by ammonium sulfate precipitation

Specificity

Recognizes human GUCY1A2.

References

1.Baba, H., et al., Neuroreport 15(4):677-680 (2004). 2.Bellamy, T.C., et al., Proc. Natl. Acad. Sci. USA 99(1):507-510 (2002). 3.Russwurm, M., et al., J. Biol. Chem. 276(48):44647-44652 (2001). 4.Bamberger, A.M., et al., J. Clin. Endocrinol. Metab. 86(2):909-912 (2001). 5.Budworth, J., et al., Biochem. Biophys. Res. Commun. 263(3):696-701 (1999).

USBio References

No references available

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G9804-47 Rabbit Anti-Guanylate Cyclase alpha-2, Soluble, CT (Guanylate Cyclase Soluble Subunit alpha-2, Guanylate Cyclase 1 Soluble alpha 2, GCS-alpha-2, GC-SA2, GUC1A2, GUCSA2, GUCY1A2)

Clone Type

Host

Source

Isotype

Grade

Applications

Crossreactivity

Accession #

Shipping Temp

Storage Temp

EC=4.6.1.2

References

USBio References

Conjugates

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