The TCR gamma, delta heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains.1 It is expressed during thymopoiesis and on the small subpopulation of gamma, delta TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are gamma, delta+ and have limited receptor diversity.1, 2 The TCR gamma, delta heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.3