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002883 Artesunate-d4 CAS: 1316753-15-7

Specifications
References
CAS Number
1316753-15-7
Grade
Highly Purified
Molecular Formula
C₁₉H₂₄D₄O₈
Molecular Weight
388.45
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester-d4; Artesunic Acid-d4

Labeled derivative of Artemisinin. Antimalarial.

Synonyms
Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester-d4; Artesunic Acid-d4
CAS No
1316753-15-7
Molecular Formula
C₁₉H₂₄D₄O₈
Molecular Weight
388.45
Appearance
Supplied as a white solid
Melting Point
130-132°C
Solubility
Chloroform (Slightly), Methanol (Slightly)
Method for Determining Identity
Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
SiO2;Dichloromethane: Methanol: 9:1; Visualized with AMCS and UV; Single spot, Rf=0.60
Elemental Analysis
Calculated: %C: 58.75, %H: 7.27
Normalized Intensity
d0=0.27%, d1=0.45%; d2=1.08%; d3=3.96%, d4=8.91%; d5=94.24%
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Store under inert atmosphere.
References
1. Zhao, Y., et al.: J. Nat. Prod., 49, 139 (1986). 2. Lin, A.J., et al.: J. Med. Chem., 30, 2147 (1987). 3. Price, R. N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000).
USBio References
No references available
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