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031477 ABCC3, ID (ABCC3, CMOAT2, MLP2, MRP3, Canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, Multi-specific organic anion transporter D, Multidrug resistance-associated protein 3) CAS:

Specifications
References
Grade
Affinity Purified
Gene ID
8714
Gene #
ABCC3
Accession Number
NP_003777.2; NP_001137542.1; O15438
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
-20°C
ABCC3, CMOAT2, MLP2, MRP3, Canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, Multi-specific organic anion transporter D, Multidrug resistance-associated protein 3

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Hoffman, A.D., et al. Protein J. 29(5):373-379(2010)|Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Moyer, A.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(3):811-821(2010)
USBio References
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