MK-571 sodium salt CAS 115104-28-4

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045035 MK-571 sodium salt CAS: 115104-28-4

Specifications

References

CAS Number

115104-28-4

Grade

Highly Purified

MDL Number

MFCD11114392

Molecular Formula

C26H26ClN2O3S2 . Na

Molecular Weight

537.1

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

4°C/-20°C

Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor. Antinociceptive.

CAS Number

115103-85-0, 115104-28-4 (free base)

Molecular Weight

537.1

Molecular Formula

C26H26ClN2O3S2●Na

Solubility

Water (20mg/ml), 100% ethanol (10mg/ml), DMSO or methanol

Appearance

Supplied as a light yellow solid.

Method for Determining Identity

Proton NMR

Purity

≥97% (NMR)

Storage and Stability

Store at -20°C under inert atmosphere. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

1. Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist: T.R. Jones, et al.; Can. J. Physiol. Pharmacol. 67, 17 (1989)|2. The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance: V. Gekeler, et al.; BBRC 208, 345 (1995)|3. The antinociceptive effect of leukotriene D(4) receptor antagonist, MK-571, in mice: possible involvement of opioidergic mechanism: Eur. J. Pharmacol. 386, 195 (1999)