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036243 GPR39, CT (GPR39, G-protein coupled receptor 39)

Specifications
References
Grade
Affinity Purified
Specificity
Human
Gene ID
2863
Gene #
GPR39
Applications
E WB
Accession Number
O43194; NP_001499.1
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
-20°C
GPR39, G-protein coupled receptor 39

Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
References
Sharir, H., et al. J. Biol. Chem. 285(34):26097-26106(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Holst, B., et al. J. Biol. Chem. 285(6):3973-3985(2010)|Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :|Zhang, Y., et al. J. Endocrinol. 199(3):457-470(2008)
USBio References
No references available
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