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I1890-32A-ML550 IgA, Secretory Component (MaxLight 550)

Specifications
References
Brand
MaxLight™
Conjugate
MaxLight™550
Specificity
Recognizes human secretory-piece and secretory IgA. No reaction against myeloma IgA (native or reduced and alkylated). Negative against normal human IgM, myeloma IgM, normal human IgG; free kappa or gamma chains and J-chain. Typical pattern on frozen and paraffin embedded sections of intestinal and breast tissue.
Source Antibody
human
Purity
Purified by Protein A affinity chromatography from ascites.
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free
BSA Free

MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000.

IgA is the most abundant immunoglobulin in body fluids and the second most abundant immunoglobulin in plasma, found at a concentration of 0.4 to 2.2mg/ml. It plays a very important role in the first specific defense against natural infection. Secretory IgA differs from serum IgA in that it contains two additional peptides: the secretory component and the J chain.
Applications
Suitable for use in Immunohistochemistry and FLISA. Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry: Frozen and Paraffin sections Optimal working dilutions to be determined by researcher.
Hybridoma
NS1 myeloma cells with spleen cells from Balb/c mice.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
References
1. Baldas, V. et al. (2004) Testing for anti-human transglutaminase antibodies in saliva is not useful for diagnosis of celiac disease. Clin Chem. 50: 216-9.
USBio References
No references available
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