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A0910 AEBSF Hydrochloride CAS: 30827-99-7

Specifications
References
CAS Number
30827-99-7
Grade
Molecular Biology Grade
MDL Number
MFCD00132962
Molecular Formula
C8H10FNO2S•HCl
Molecular Weight
239.69
EU Commodity Code
38220090
UN DOT Shipping
UN3261 PGII
Shipping Temp
RT
Storage Temp
4°C
4-(2-Aminoethyl)-bezenesulfonylfluoride•HCl

Specific irreversible inhibitor of serine proteases such as thrombin, plasmin, kallikrein, chymotrypsin and trypsin. It is a non-toxic alternative to PMSF or DFP. AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25mM.

Synonyms
4-(2-Aminoethyl)-bezenesulfonylfluoride•HCl
CAS No
30827-99-7
Molecular Formula
C8H10FNO2S•HCl
Molecular Weight
239.69
Appearance
White to off-white powder.
Purity
≥98% (1H NMR)
Solubility
Colorless, clear, complete in water. H2O: soluble, 50mg/ml (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.)
Storage and Stability
May be stored at 4°C Stable for 12 months after receipt. Hygroscopic. Keep tightly closed and desiccated. Light sensitive.
References
1. Sastalla, I. et al., (2013) PLoS One 8(10): e76955. doi:10.1371/journal.pone.0076955. 1. Walsmann, P., et al., Acta biol. med. germ. 28: 577-585 (1972). 2. Marwardt, F., et al., Thrombosis Res. 2: 343-348 (1973). 3. Taylor, J.A., et al., Immunology 86: 629-635 (1995). 3. Pomerantsev AP, et al. Genome engineering in Bacillus anthracis using tyrosine site-specific recombinases. PLoS One. 2017 Aug 22;12(8):e0183346. doi: 10.1371/journal.pone.0183346. eCollection 2017.
USBio References
1. Sastalla, I. et al., (2013) PLoS One 8(10): e76955. doi:10.1371/journal.pone.0076955. 2. Pomerantsev AP, et al. Genome engineering in Bacillus anthracis using tyrosine site-specific recombinases. PLoS One. 2017 Aug 22;12(8):e0183346. doi: 10.1371/journal.pone.0183346. eCollection 2017.
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